Get to know! “Premature aging“, a disease of abnormal cells in one in a million
Premature aging, childhood aging, or Hudchinson-Gilford progeria syndrome is very rare, affecting only 1 in 8 million people worldwide. 90% of children with this disease are caused by mutations in the Lmna gene, which causes abnormal synthesis of the laminA protein. This disease is caused by abnormalities in cells and genes in the body that age more than normal. At birth, children may be born with only a little less weight than normal, but their physical and brain growth and development will start to slow down significantly from the age of 1-2 years onwards.
Today, we have symptoms of “premature aging” for everyone.
- They grow very slowly, are stunted, short, underweight, age quickly, and tire easily.
- Wrinkled skin, appearance much older than actual age, shrill voice
- The skull is thin and disproportionate, and the face and jaw are smaller than normal.
- Hair and body hair fall out, teeth grow slowly and fall out easily, abnormal nails such as thin, short nails or no nails, osteoporosis and often have pain in the joints.
- They usually die at an average age of about 13 years from abnormalities in the heart and other organs that deteriorate, such as heart failure and cerebral atherosclerosis.
At present, there is still no way to find a 100% cure for Progeria. All we can do is support the symptoms and overall health of the patient or do Lmna testing to examine at the molecular level of pregnant women. There may be little prevention, but physical examination of the parents and planning before having children may help detect some abnormalities in the cells in the parents’ bodies that may affect the child, but it is not possible to confirm every disease 100%.
Signs of Premature Aging
Although there’s no evidence to prove this, it’s believed that premature aging commonly occurs after the age of 40. But the truth ทางเข้า ufabet https://ufabet999.app is that it can happen anytime during adulthood. In fact, aging begins in your 20s, when collagen production starts reducing gradually. But you won’t notice any symptoms right from the beginning. After a few years, your body will start showing visible signs of aging. If you see these indicators earlier, you can act quickly to prevent premature aging. So here are some signs of aging that you should look for:
- The skin exhibits the most prevalent and apparent indications of aging. You might notice wrinkles in the corner of your eyes, dry and dehydrated skin, skin sagging, sunken cheeks, and uneven skin tone.
- Hyperpigmentation is also a common sign of aging especially around your chest.
- You might find it difficult to see, hear, and retain information.
- Hair loss, balding, and greying of the hair some signs of premature aging. You can spot on your scalp and hair.
- Premature aging can also affect your digestive system due to disbalance in the gut microbiota, causing issues like constipation, diarrhea, heartburn, bloating, etc.